Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31137435 | 1.00 | LPL (0.38) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL31137693 | 0.91 | EGFR (0.38) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL1397094 | 0.91 | EGFR (0.38) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL23540948 | 0.91 | EGFR (0.38) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL1397050 | 0.87 | LPL (0.35) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL21067071 | 0.86 | GAA (0.35) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL28511283 | 0.86 | LPL (0.34) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL25277938 | 0.86 | GAA (0.35) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL1646761 | 0.86 | LPL (0.44) | LPLLIPGEGFRJAK2BTK | |
| SCHEMBL27192332 | 0.85 | LPL (0.38) | LPLLIPGEGFRJAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12466803-B2 | BCKDK inhibitors and/or degraders | PFIZER INC. (US) | 2025-11-11 | — | — | US | disclosed |
| EP-4610260-A1 | ARYL HETEROCYCLIC KV1.3 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shanghai Shenshi Wise Technology Co., Ltd. (CN) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088343-A1 | ARYL HETEROCYCLIC KV1.3 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海深势唯思科技有限责任公司 | 2024-05-02 | — | — | WO | disclosed |
| CN-117946111-A | Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023100061-A1 | 3-PHENYL-1-BENZOTHIOPHENE-2-CARBOXYLIC ACID DERIVATIVES AS BRANCHED-CHAIN ALPHA KETO ACID DEHYDROGENASE KINASE INHIBITORS FOR THE TREATMENT OF DIABETES, KIDNEY DISEASES, NASH AND HEART FAILURE | PFIZER INC. (US) | 2023-06-08 | — | — | WO | disclosed |
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2023-06-01 | — | — | US | disclosed |
| EP-2573074-B1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8598085-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2573074-A1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | disclosed |
| EP-2311815-B1 | 2-(2-Fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2176239-B1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| US-7915200-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | LPL 4188/4885LIPG 4532/4885EGFR 1509/4885 |
| US-12466803-B2 | BCKDK inhibitors and/or degraders | BCKDK, KHK, PDK4 | LPL 704/4885LIPG 455/4885EGFR 833/4885 |
| US-20230167080-A1 | BCKDK INHIBITORS AND/OR DEGRADERS | BCKDK, KHK, PDK4 | LPL 704/4885LIPG 455/4885EGFR 833/4885 |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | LPL 4234/4885LIPG 4560/4885EGFR 1572/4885 |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | LPL 4188/4885LIPG 4532/4885EGFR 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.