Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.44 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14778479 | 1.00 | ALOX15 (0.44) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL220326 | 0.87 | CYP3A4 (0.52) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL218706 | 0.78 | ALOX15 (0.43) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL974579 | 0.76 | REN (0.52) | — | |
| SCHEMBL974581 | 0.76 | REN (0.52) | — | |
| Terameprocol SCHEMBL194588 | 0.69 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL2356280 | 0.69 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL10060164 | 0.69 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL29794162 | 0.69 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN | |
| Terameprocol SCHEMBL30094578 | 0.69 | ALOX15 (0.77) | ALOX15ALOX12FOSTTRJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346745-B2 | Process for producing Aliskiren | CHEMO IBERICA, S.A. (ES) | 2016-05-24 | — | — | US | disclosed |
| US-20130071899-A1 | Process for Producing Aliskiren | CHEMO IBERICA, S.A. (ES) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071899-A1 | Process for Producing Aliskiren | REN, AGTR1, AGTR2 | ALOX15 506/4885ALOX12 710/4885FOS 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.