Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | F3 | P13726 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092085 | 0.90 | LMNA (0.67) | LMNATDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8155177 | 0.87 | LMNA (0.58) | LMNATDP1MAPTKMT2AGFER | |
| SCHEMBL12607364 | 0.86 | NPC1 (0.52) | LMNAMAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL8158920 | 0.84 | LMNA (0.54) | LMNATDP1MAPTKMT2AGFER | |
| SCHEMBL3610592 | 0.84 | MAPT (0.57) | LMNATDP1MAPTKMT2AGFER | |
| SCHEMBL7690738 | 0.84 | MAPT (0.61) | LMNAMAPTKMT2AGFERKDM4E | |
| SCHEMBL7690737 | 0.84 | MAPT (0.61) | LMNAMAPTKMT2AGFERKDM4E | |
| SCHEMBL16379481 | 0.84 | LMNA (0.51) | LMNATDP1MAPTKMT2AGFER | |
| SCHEMBL18993858 | 0.83 | LMNA (0.55) | LMNATDP1MAPTKMT2AGFER | |
| SCHEMBL16379485 | 0.82 | LMNA (0.52) | LMNATDP1MAPTKMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399068-B2 | Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device | JSR CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |