Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14780856 | 0.90 | LMNA (0.56) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL8148439 | 0.87 | LMNA (0.68) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL252040 | 0.85 | LMNA (0.62) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL5403708 | 0.85 | LMNA (0.62) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL10624482 | 0.85 | LMNA (0.70) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL8428926 | 0.84 | LMNA (0.65) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL8428924 | 0.84 | LMNA (0.65) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL39355 | 0.84 | LMNA (0.72) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL7890638 | 0.84 | LMNA (0.72) | LMNATDP1SMN1; SMN2GSK3BF3 | |
| SCHEMBL21294324 | 0.84 | LMNA (0.72) | LMNATDP1SMN1; SMN2GSK3BF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399068-B2 | Liquid crystal aligning agent, method of producing a liquid crystal alignment film and liquid crystal display device | JSR CORPORATION (JP) | 2013-03-19 | — | — | US | disclosed |
| US-20030092865-A1 | Silicone based ultraviolet absorbing and/or scattering compounds and associated formulations comprising the same | SILVER MICHAEL E (US) | 2003-05-15 | — | — | US | disclosed |