SCHEMBL14780876

SCHEMBL14780876

CNc1cc(C2=NOC(c3cc(Cl)cc(CI)c3)(C(F)(F)F)C2)ccc1Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472307 0.90 CA1 (0.33) KDM4EMAPT
SCHEMBL10132523 0.86 KDM4E (0.32) KDM4EMAPT
SCHEMBL472298 0.80 CA1 (0.31)
SCHEMBL14780888 0.80 PDE3B (0.33)
SCHEMBL27911168 0.78 KDM4E (0.33) KDM4EMAPT
SCHEMBL10039281 0.78 RAB9A (0.40)
SCHEMBL16508607 0.77 CA1 (0.34)
SCHEMBL566522 0.77 CA1 (0.35) KDM4EMAPT
SCHEMBL3359275 0.76 PDE3B (0.40) KDM4EMAPT
SCHEMBL1547842 0.76 CA1 (0.35) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399498-B2 Animal ectoparasite-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed