SCHEMBL566522

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL472296	0.91	PDK1 (0.36)	CA1CA2LMNAMAPTKCNJ6
	SCHEMBL10039281	0.91	RAB9A (0.40)	CA1CA2LMNAPDK1PDK2
	SCHEMBL10039199	0.89	MEN1 (0.45)	MAPTMEN1KMT2ATP53CYP2C19
	SCHEMBL1547842	0.89	CA1 (0.35)	CA1CA2MAPTPDK1PDK2
	SCHEMBL13299438	0.88	MEN1 (0.34)	CA1CA2LMNAMEN1KMT2A
	SCHEMBL10039214	0.87	HSP90AA1 (0.34)	CA1CA2PDK1PDK2PDK3
	SCHEMBL472622	0.85	CA1 (0.33)	CA1CA2MAPTMEN1KMT2A
	SCHEMBL472295	0.85	CA1 (0.35)	CA1CA2MEN1KMT2AF10
	SCHEMBL472298	0.85	CA1 (0.31)	CA1CA2
	SCHEMBL472307	0.85	CA1 (0.33)	CA1CA2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.