Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039214 | 0.89 | HSP90AA1 (0.34) | PDE3BPDE3ACYP17A1AAK1F10 | |
| SCHEMBL16384771 | 0.88 | CYP17A1 (0.34) | PDE3BPDE3ACYP17A1CDK9AAK1 | |
| SCHEMBL10132744 | 0.87 | PDK1 (0.34) | PDE3BPDE3ACYP17A1AAK1F10 | |
| SCHEMBL10144373 | 0.86 | PDK1 (0.35) | PDE3BPDE3ACYP17A1AAK1F10 | |
| SCHEMBL14780877 | 0.82 | — | — | |
| SCHEMBL1547842 | 0.81 | CA1 (0.35) | F10F2PDK1PDK2PDK3 | |
| SCHEMBL14780876 | 0.80 | KDM4E (0.30) | — | |
| SCHEMBL10039281 | 0.77 | RAB9A (0.40) | F10F2PDK1PDK2PDK3 | |
| SCHEMBL2516410 | 0.76 | PDE3B (0.36) | PDE3BPDE3A | |
| SCHEMBL6241193 | 0.76 | DRD2 (0.36) | CYP17A1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399498-B2 | Animal ectoparasite-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-03-19 | — | — | US | disclosed |