Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 6/20 | 0.34 |
| ▸ | CA1 | P00915 | 6/20 | 0.34 |
| ▸ | CA2 | P00918 | 6/20 | 0.34 |
| ▸ | CA7 | P43166 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 6/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267993 | 0.82 | MAPT (0.41) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL3114046 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL21044540 | 0.72 | MAPK1 (0.42) | ALDH1A1MAPTLMNANPC1RAB9A | |
| SCHEMBL31427618 | 0.69 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL31427607 | 0.69 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL20888481 | 0.66 | LMNA (0.42) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL14479758 | 0.66 | ALDH1A1 (0.34) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL11648212 | 0.65 | CA12 (0.44) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL23471197 | 0.64 | CA12 (0.51) | ALDH1A1MAPTLMNACA12CA1 | |
| SCHEMBL9637797 | 0.63 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399489-B2 | Antibacterial piperdine derivatives | ASTRAZENECA AB (GB) | 2013-03-19 | — | — | US | disclosed |