Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | SI | P14410 | 1/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27742042 | 0.90 | LMNA (0.50) | MGAMGAASIMGAM2POLB | |
| Toluene SCHEMBL28153542 | 0.85 | LMNA (0.55) | POLBNPC1RAB9AMEN1KMT2A | |
| Toluene SCHEMBL8882403 | 0.85 | GAA (0.50) | MGAMGAASIMGAM2NPC1 | |
| Toluene SCHEMBL27945492 | 0.84 | POLB (0.46) | POLBNPC1RAB9AMEN1KMT2A | |
| Phenol SCHEMBL11702329 | 0.84 | MGAM (0.60) | MGAMGAASIMGAM2POLB | |
| Toluene SCHEMBL2598282 | 0.83 | LMNA (0.52) | POLBNPC1RAB9AMEN1KMT2A | |
| Toluene SCHEMBL28361943 | 0.83 | LMNA (0.52) | POLBNPC1RAB9AMEN1KMT2A | |
| Toluene SCHEMBL29105779 | 0.82 | MTNR1A (0.41) | MGAMGAASIMGAM2POLB | |
| Toluene SCHEMBL27324786 | 0.82 | POLB (0.47) | GAAPOLBNPC1RAB9AMEN1 | |
| Acetoacetic Acid SCHEMBL9704495 | 0.81 | NPC1 (0.50) | POLBNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214355-B | A kind of method prepared containing methyl fluoride or aryl alkyl ketone | JIANGSU ZHONGDAN PHARMACEUTICAL RESEARCH Co.,Ltd. (CN) | 2016-02-17 | — | — | CN | disclosed |
| US-20150346209-A1 | METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES | UNIV WAKE FOREST HEALTH SCIENCES (US) | 2015-12-03 | — | — | US | disclosed |
| US-9023653-B2 | Method of labeling sulfenic acid-containing proteins and peptides | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2015-05-05 | — | — | US | disclosed |
| CN-103214355-A | Method for preparing fluorine-containing methyl or alkylaryl ketones | JIANGSU ZHONGDAN PHARMACEUTICAL RES CO LTD | 2013-07-24 | — | — | CN | disclosed |
| US-20130149732-A1 | METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES | FURDUI CRISTINA M (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2013039717-A2 | METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2013-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150346209-A1 | METHOD OF LABELING SULFENIC ACID-CONTAINING PROTEINS AND PEPTIDES | CTH, PTMS, CBS | MGAM 2891/4885GAA 3198/4885SI 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.