⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1478312 | 0.84 | MAPT (0.31) | — | |
| SCHEMBL1478096 | 0.79 | CA12 (0.33) | — | |
| SCHEMBL1478754 | 0.78 | NOTUM (0.36) | — | |
| SCHEMBL11897254 | 0.76 | HPGD (0.31) | — | |
| SCHEMBL1478777 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL1479438 | 0.73 | ALDH1A1 (0.31) | — | |
| SCHEMBL3691267 | 0.70 | HPGD (0.58) | — | |
| SCHEMBL21630202 | 0.70 | MEN1 (0.50) | — | |
| SCHEMBL3686294 | 0.68 | MAPT (0.48) | — | |
| SCHEMBL610351 | 0.68 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | claimed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | claimed |
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2483317-B1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-20120184677-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |