Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460883 | 0.84 | CA1 (0.44) | ALDH1A1HPGDMAPTCA1CA2 | |
| SCHEMBL1478516 | 0.84 | ALDH1A1 (0.38) | NOTUMALDH1A1HPGDMAPTCA1 | |
| SCHEMBL1478847 | 0.79 | CA1 (0.58) | ALDH1A1HPGDMAPTCA1CA2 | |
| SCHEMBL5051772 | 0.79 | TPMT (0.46) | CA1CA2CA12CA7CA9 | |
| SCHEMBL12212913 | 0.78 | PDCD1 (0.46) | ALDH1A1HPGDMAPTCA1CA2 | |
| SCHEMBL3691267 | 0.78 | HPGD (0.58) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL1478660 | 0.78 | — | — | |
| SCHEMBL3686294 | 0.76 | MAPT (0.48) | ALDH1A1HPGDMAPTTDP1KDM4E | |
| SCHEMBL10917868 | 0.76 | HPGD (0.54) | ALDH1A1HPGDMAPTCA1CA2 | |
| SCHEMBL10931509 | 0.76 | CA12 (0.59) | ALDH1A1HPGDMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | claimed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | claimed |
| US-8895670-B2 | Functionalized polymers and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2483317-B1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2014-02-26 | — | — | EP | disclosed |
| US-20120184677-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2012-07-19 | — | — | US | disclosed |
| US-20110077325-A1 | FUNCTIONALIZED POLYMERS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-03-31 | — | — | US | disclosed |