SCHEMBL1478690

SCHEMBL1478690

CON(C)C(=O)c1cc(Br)cnc1N

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
HTT P42858 1/20 0.41
PIK3C3 Q8NEB9 1/20 0.36
OPRK1 P41145 4/20 0.36
MEN1 O00255 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
PIK3CA P42336 3/20 0.35
MTOR P42345 3/20 0.35
SHMT2 P34897 1/20 0.34
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1516575 0.98 KMT2A (0.40) KMT2AHTTPIK3C3OPRK1MEN1
SCHEMBL857401 0.84 PIK3C3 (0.48) KMT2AHTTPIK3C3OPRK1KDM4E
SCHEMBL21591708 0.83 OPRK1 (0.37) KMT2APIK3C3OPRK1MEN1TDP1
SCHEMBL30041415 0.83 OPRK1 (0.37) KMT2APIK3C3OPRK1MEN1TDP1
SCHEMBL11968535 0.83 NOS3 (0.42) PIK3C3PIK3CAMTOR
SCHEMBL1599853 0.82 ALDH1A1 (0.40) KMT2APIK3C3OPRK1MEN1TDP1
SCHEMBL2628501 0.82 PIK3C3 (0.40) KMT2APIK3C3OPRK1MEN1TDP1
SCHEMBL29915138 0.82 ALDH1A1 (0.40) KMT2APIK3C3OPRK1MEN1TDP1
SCHEMBL19100681 0.79 PIK3C3 (0.39) KMT2APIK3C3OPRK1MEN1TDP1
SCHEMBL23705904 0.78 PIK3CA (0.35) KMT2APIK3C3OPRK1MEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115835909-B Cannabinoid receptor type 2 (CB 2) modulators and uses thereof 泰昂治疗公司 2026-05-15 CN disclosed
US-20240252504-A1 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF TEON THERAPEUTICS INC (US) 2024-08-01 US disclosed
US-11957689-B2 Cannabinoid receptor type 2 (CB2) modulators and uses thereof TEON THERAPEUTICS, INC. (US) 2024-04-16 US disclosed
US-20230143502-A1 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF TEON THERAPEUTICS, INC 2023-05-11 US disclosed
US-20230143502-A1 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF TEON THERAPEUTICS, INC 2023-05-11 US disclosed
US-20230143502-A1 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF TEON THERAPEUTICS, INC 2023-05-11 US disclosed
CN-115835909-A Cannabinoid receptor type 2 (CB 2) modulators and uses thereof 泰昂治疗公司 2023-03-21 CN disclosed
EP-4146345-A2 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF Teon Therapeutics, Inc. (US) 2023-03-15 EP disclosed
US-11564928-B1 Cannabinoid receptor type 2 (CB2) modulators and uses thereof TEON THERAPEUTICS, INC. (US) 2023-01-31 US disclosed
US-11564928-B1 Cannabinoid receptor type 2 (CB2) modulators and uses thereof TEON THERAPEUTICS, INC. (US) 2023-01-31 US disclosed
US-7361763-B2 Pyrrolo-pyridine kinase modulators SGX PHARMACEUTICALS, INC. (US) 2008-04-22 US disclosed
US-7361764-B2 Pyrrolo-pyridine kinase modulators SGX PHARMACEUTICALS, INC. (US) 2008-04-22 US disclosed
WO-2007106236-A2 PYRROLO-PYRIDINE KINASE MODULATORS SGX PHARMACEUTICALS, INC. (US) 2007-09-20 WO disclosed
WO-2007106236-A2 PYRROLO-PYRIDINE KINASE MODULATORS SGX PHARMACEUTICALS, INC. (US) 2007-09-20 WO disclosed
EP-1781654-A1 PYRROLO-PYRIDINE KINASE MODULATORS SGX Pharmaceuticals, Inc. (US) 2007-05-09 EP disclosed
US-20070043068-A1 to treat diseases mediated by kinase activity; for example: [3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-methyl-phenyl-amine SGX PHARMACEUTICALS, INC. (US) 2007-02-22 US disclosed
US-20070043068-A1 to treat diseases mediated by kinase activity; for example: [3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-methyl-phenyl-amine SGX PHARMACEUTICALS, INC. (US) 2007-02-22 US disclosed
US-20070043068-A1 to treat diseases mediated by kinase activity; for example: [3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-methyl-phenyl-amine SGX PHARMACEUTICALS, INC. (US) 2007-02-22 US disclosed
US-20060030583-A1 Pyrrolo-pyridine kinase modulators SGX PHARMACEUTICALS, INC. (US) 2006-02-09 US disclosed
WO-2006015123-A1 PYRROLO-PYRIDINE KINASE MODULATORS SGX PHARMACEUTICALS, INC. (US) 2006-02-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143502-A1 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF CNR2, CNR1, GPR18 KMT2A 2205/4885HTT 2855/4885PIK3C3 2955/4885
US-11564928-B1 Cannabinoid receptor type 2 (CB2) modulators and uses thereof CNR2, CNR1, GPR18 KMT2A 2205/4885HTT 2855/4885PIK3C3 2955/4885
US-20060030583-A1 Pyrrolo-pyridine kinase modulators MAP3K20, MAP4K2, MAP3K19 KMT2A 1322/4885HTT 2856/4885PIK3C3 595/4885
US-20240252504-A1 CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF CNR2, CNR1, GPR18 KMT2A 2205/4885HTT 2855/4885PIK3C3 2955/4885
US-11957689-B2 Cannabinoid receptor type 2 (CB2) modulators and uses thereof CNR2, CNR1, GPR18 KMT2A 2205/4885HTT 2855/4885PIK3C3 2955/4885
US-20070043068-A1 to treat diseases mediated by kinase activity; for example: [3-(2-methoxy-phenyl)-1H-pyrrolo[2,3-b]pyridine-5-yl]-methyl-phenyl-amine MAP3K20, MAP4K2, MAP3K6 KMT2A 975/4885HTT 2554/4885PIK3C3 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.