SCHEMBL8460883

SCHEMBL8460883

C[Si](C)(C)OC(=O)c1ccc(C(=O)O[Si](C)(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA12 O43570 3/20 0.44
CA7 P43166 3/20 0.44
CA9 Q16790 3/20 0.44
CA14 Q9ULX7 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
TSHR P16473 3/20 0.41
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
ESR1 P03372 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ESR2 Q92731 1/20 0.40
HPGD P15428 1/20 0.39
LMNA P02545 3/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAOA P21397 1/20 0.39
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12212913 0.93 PDCD1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL10931509 0.91 CA12 (0.59) CA1CA2CA12CA7CA9
SCHEMBL10917868 0.91 HPGD (0.54) CA1CA2CA12CA7CA9
SCHEMBL11091381 0.89 ALDH1A1 (0.50) CA1CA2TSHRALDH1A1MAPT
SCHEMBL10392651 0.89 LMNA (0.55) TSHRALDH1A1MAPTLMNACYP1A2
SCHEMBL5051772 0.89 TPMT (0.46) CA1CA2CA12CA7CA9
SCHEMBL1759366 0.88 TSHR (0.58) TDP1TSHRALDH1A1MAPTLMNA
SCHEMBL11081790 0.87 CA1 (0.64) CA1CA2MAPTKDM4ELMNA
SCHEMBL9806223 0.85 ALDH1A1 (0.63) ALDH1A1MAPTKDM4EKMT2A
SCHEMBL12213023 0.84 PTPN11 (0.45) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3352281-B1 NON-AQUEOUS ELECTROLYTE SOLUTION AND NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY ADEKA CORP (JP) 2021-08-11 EP disclosed
EP-3054521-B1 ELECTROLYTE AND LITHIUM-ION SECONDARY BATTERY ASAHI CHEMICAL IND (JP) 2021-06-16 EP disclosed
CN-108140887-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery 株式会社艾迪科 2021-03-12 CN disclosed
CN-105745779-B Composition for addition to electrolyte solution containing silyl group-containing compound, electrolyte solution, and lithium ion secondary battery 旭化成株式会社 2021-02-05 CN disclosed
US-10734684-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery ADEKA CORPORATION (JP) 2020-08-04 US disclosed
CN-107210489-B Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery 株式会社艾迪科 2020-03-20 CN disclosed
EP-3038201-B1 COMPOSITION FOR ADDITION TO ELECTROLYTE SOLUTIONS CONTAINING SILYL GROUP-CONTAINING COMPOUND, ELECTROLYTE SOLUTION FOR NONAQUEOUS ELECTRICITY STORAGE DEVICES CONTAINING SAID COMPOSITION, AND LITHIUM ION SECONDARY BATTERY CONTAINING SAID ELECTROLYTE SOLUTION ASAHI CHEMICAL IND (JP) 2019-10-30 EP disclosed
US-10388989-B2 Non-aqueous electrolyte, and non-aqueous electrolyte secondary cell ADEKA CORPORATION (JP) 2019-08-20 US disclosed
US-20180226683-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROPLYTE SECONDARY BATTERY ADKEA CORPORATION (JP) 2018-08-09 US disclosed
EP-3352281-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Adeka Corporation (JP) 2018-07-25 EP disclosed
EP-2879144-A1 ELECTRICITY STORAGE DEVICE Adeka Corporation (JP) 2015-06-03 EP disclosed
US-20150044551-A1 NONAQUEOUS SECONDARY BATTERY ADEKA CORPORATION (JP) 2015-02-12 US disclosed
EP-2775559-A1 NON-AQUEOUS ELECTROLYTE SECONDARY BATTERY Adeka Corporation (JP) 2014-09-10 EP disclosed
EP-0641832-B1 Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof DOW CORNING ASIA LTD (JP) 1999-01-13 EP disclosed
EP-0641831-B1 Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA LTD (JP) 1997-11-12 EP disclosed
US-5527862-A COMPATIBLE BLENDS; REINFORCED CURED COMPOSITES; HIGH STRENGTH DOW CORNING ASIA, LTD. (JP) 1996-06-18 US disclosed
US-5464922-A Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA LTD. (JP) 1995-11-07 US disclosed
EP-0641832-A1 Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof DOW CORNING ASIA, Ltd. (JP) 1995-03-08 EP disclosed
EP-0641831-A1 Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same DOW CORNING ASIA, Ltd. (JP) 1995-03-08 EP disclosed
US-4470932-A TRIMETHYL SILYL CARBOXYLATE AND CARBOXYLIC ACID CHLORIDE BAYER AKTIENGESELLSCHAFT (DE) 1984-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180226683-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROPLYTE SECONDARY BATTERY SLC9A1, SLC8A1, KCNN1 CA1 286/4885CA2 393/4885CA12 516/4885
US-10734684-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte secondary battery KCNN1, KCNN2, SLC9A1 CA1 115/4885CA2 201/4885CA12 252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.