Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489204 | 0.93 | LMNA (0.69) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL15784537 | 0.88 | LMNA (0.54) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL20151955 | 0.87 | SMN1; SMN2 (0.53) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL25366061 | 0.84 | MEN1 (0.49) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL7682044 | 0.84 | LMNA (0.69) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14288938 | 0.84 | LMNA (0.69) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18101226 | 0.83 | LMNA (0.57) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL18743948 | 0.83 | LMNA (0.49) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL16589855 | 0.83 | LMNA (0.58) | LMNAKDM4EMEN1KMT2AHPGD | |
| SCHEMBL11957306 | 0.82 | HPGD (0.59) | LMNAKDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130071482-A1 | BLOCK COPOLYMER CROSS-LINKED NANOASSEMBLIES AS MODULAR DELIVERY VEHICLES | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2013-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130071482-A1 | BLOCK COPOLYMER CROSS-LINKED NANOASSEMBLIES AS MODULAR DELIVERY VEHICLES | SDCBP, PSMB6, BAG2 | LMNA 3767/4885KDM4E 3992/4885MEN1 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.