Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP13 | P45452 | 4/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679340 | 0.71 | LOXL2 (0.46) | KDM4ELMNAMEN1HTTKMT2A | |
| SCHEMBL27690179 | 0.71 | AKR1B1 (0.51) | MEN1KMT2AALDH1A1HSD17B10MAPT | |
| SCHEMBL4507525 | 0.71 | AKR1B1 (0.51) | MEN1KMT2AALDH1A1MAPTPGR | |
| SCHEMBL128402 | 0.69 | LOXL2 (0.61) | MEN1KMT2ASMN1; SMN2ALDH1A1LOXL2 | |
| Barbital SCHEMBL43818 | 0.69 | LMNA (1.00) | KDM4EMMP8LMNASMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL4739223 | 0.68 | LOXL2 (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1LOXL2 | |
| Bromide SCHEMBL2771283 | 0.68 | LOXL2 (0.59) | MEN1KMT2ASMN1; SMN2ALDH1A1LOXL2 | |
| SCHEMBL14782921 | 0.68 | LMNA (0.47) | MMP8LMNAALDH1A1MMP2MMP9 | |
| SCHEMBL14782806 | 0.68 | LMNA (0.47) | KDM4EMMP8LMNAALDH1A1MMP2 | |
| SCHEMBL1204527 | 0.67 | LOXL2 (0.48) | KDM4ELMNASMN1; SMN2ALDH1A1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013038153-A1 | 18F-LABELLED BARBITURATE COMPOUNDS FOR USE AS POSITRON EMISSION IMAGING AGENTS | THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) | 2013-03-21 | — | — | WO | disclosed |