Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15723894 | 0.76 | LMNA (0.33) | — | |
| SCHEMBL14793320 | 0.75 | QRFPR (0.48) | KMT2APARP14QRFPR | |
| SCHEMBL14785262 | 0.75 | EPHX1 (0.37) | EPHX1KMT2APARP14 | |
| SCHEMBL28370073 | 0.72 | KMT2A (0.41) | KMT2AQRFPR | |
| SCHEMBL14785329 | 0.72 | CXCR4 (0.34) | EPHX1KMT2A | |
| SCHEMBL18202491 | 0.70 | QRFPR (0.55) | EPHX1KMT2AQRFPR | |
| SCHEMBL23027747 | 0.67 | CES2 (0.33) | — | |
| SCHEMBL11957883 | 0.67 | CES2 (0.39) | — | |
| SCHEMBL8375338 | 0.63 | — | — | |
| SCHEMBL28861481 | 0.59 | ACHE (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013037894-A1 | DISUBSTITUTED 5-FLUORO PYRIMIDINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-21 | — | — | WO | disclosed |