Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297051 | 0.80 | IDO1 (0.41) | LMNADAO | |
| SCHEMBL16918931 | 0.79 | HTR3E (0.32) | DAO | |
| SCHEMBL25132526 | 0.78 | TYR (0.32) | LMNA | |
| SCHEMBL18732234 | 0.78 | NPC1 (0.30) | LMNA | |
| SCHEMBL14793323 | 0.76 | EPHX1 (0.35) | — | |
| SCHEMBL18433896 | 0.75 | NOS3 (0.37) | — | |
| SCHEMBL18387130 | 0.72 | LMNA (0.37) | LMNA | |
| SCHEMBL11957883 | 0.72 | CES2 (0.39) | — | |
| SCHEMBL23027747 | 0.72 | CES2 (0.33) | — | |
| SCHEMBL10138706 | 0.72 | NOS1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014076028-A1 | 4-(ORTHO)-FLUOROPHENYL-5-FLUOROPYRIMIDIN-2-YL AMINES CONTAINING A SULFOXIMINE GROUP | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-05-22 | — | — | WO | disclosed |