Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594859 | 0.81 | HTR1A (0.55) | ALDH1A1KDM4ENCF1LMNAHPGD | |
| SCHEMBL15789909 | 0.80 | MAPT (0.46) | ALDH1A1KDM4EMAPK1GAANPC1 | |
| Ammonia Solution, Strong SCHEMBL7896018 | 0.78 | KEAP1 (0.52) | KEAP1MAPK1NCF1GAAFABP3 | |
| SCHEMBL31556704 | 0.78 | HTR1A (0.41) | KEAP1ALDH1A1KDM4EMAPK1PTPN1 | |
| SCHEMBL6159274 | 0.76 | NCF1 (0.49) | KEAP1ALDH1A1KDM4EMAPK1NCF1 | |
| SCHEMBL6514775 | 0.76 | KEAP1 (0.53) | KEAP1MAPK1NCF1GAAFABP3 | |
| SCHEMBL28053480 | 0.76 | NCF1 (0.49) | KEAP1ALDH1A1KDM4EMAPK1NCF1 | |
| SCHEMBL2346705 | 0.74 | KEAP1 (0.52) | KEAP1ALDH1A1KDM4EMAPK1NCF1 | |
| SCHEMBL11305984 | 0.74 | KEAP1 (0.52) | KEAP1ALDH1A1KDM4EMAPK1NCF1 | |
| SCHEMBL11711744 | 0.74 | OPRL1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7915421-B2 | Method for preparing phenyl acetic acid derivatives | CILAG LTD. (CH) | 2011-03-29 | — | — | US | disclosed |
| US-20070123564-A1 | Method for preparing phenyl acetic acid derivatives | CILAG LTD. (CH) | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123564-A1 | Method for preparing phenyl acetic acid derivatives | PHF2, ASF1A, NAT1 | KEAP1 4725/4885ALDH1A1 721/4885KDM4E 1206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.