Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8406795 | 0.91 | L3MBTL1 (0.66) | CTBP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL4632976 | 0.88 | NPC1 (0.50) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL2251562 | 0.88 | RAB9A (0.50) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL28837741 | 0.87 | NPC1 (0.62) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL622333 | 0.86 | GSK3B (0.52) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL1512094 | 0.86 | NPC1 (0.48) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL3070923 | 0.86 | L3MBTL1 (0.52) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL4327956 | 0.84 | CTBP2 (0.52) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL11221142 | 0.84 | L3MBTL1 (0.58) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL1151043 | 0.84 | NPC1 (0.47) | NPC1RAB9ACTBP2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141146-A | Synthesis method of hypoglycemic active compound 1,2, 3-trimethyl-4- (p-chlorophenyl) -pyrazolium salt | 东力（南通）化工有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-117486682-A | Preparation method of functionalized beta-naphthalenyl ether compound | 中国海洋石油集团有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117486681-A | Preparation method of 3-aryl/alkyl-beta-anisole compound | 中国海洋石油集团有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2023185149-A1 | SULFONATED BENZENE POLYPHENYL IONOMER AND METHOD FOR PREPARING SAME, AND PROTON EXCHANGE MEMBRANE | 中国科学院深圳先进技术研究院 | 2023-10-05 | — | — | WO | disclosed |
| CN-115141146-A | Synthesis method of hypoglycemic active compound 1,2, 3-trimethyl-4- (p-chlorophenyl) -pyrazolium salt | 东力（南通）化工有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | BIOMARIN PHARMACEUTICAL INC. (US) | 2022-07-12 | — | — | US | disclosed |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2021-06-10 | — | — | US | disclosed |
| WO-2020257487-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2020-12-24 | — | — | WO | disclosed |
| US-20160280819-A1 | CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE | MITSUI CHEMICALS, INC. (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-1900758-B9 | METHOD FOR PRODUCING OLEFIN POLYMER | MITSUI CHEMICALS INC (JP) | 2016-07-13 | — | — | EP | disclosed |
| US-5200561-A | PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0485069-A1 | Process for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-05-13 | — | — | EP | disclosed |
| EP-0187659-B1 | PROCESS FOR GRAFTING UNSATURATED MONOMERS ON OLEFINIC POLYMERS | Montedison S.p.A. (IT) | 1989-12-27 | — | — | EP | disclosed |
| US-4624992-A | Process for grafting unsaturated monomers on olefinic polymers | AUSIMONT S.P.A. (IT) | 1986-11-25 | — | — | US | disclosed |
| EP-0187659-A2 | Process for grafting unsaturated monomers on olefinic polymers | Montedison S.p.A. (IT) | 1986-07-16 | — | — | EP | disclosed |
| US-4568490-A | REDUCTIVE CONDENSATION WITH A CARBONYL COMPOUND | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1986-02-04 | — | — | US | disclosed |
| US-4537880-A | Aminopropylaminobleomycin derivatives and process for preparation thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1985-08-27 | — | — | US | disclosed |
| US-4340756-A | Polyamine compounds as antibacterial agents | MERCK & CO., INC. (US) | 1982-07-20 | — | — | US | disclosed |
| US-4169951-A | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PYRIDINE (B) | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-02 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11384055-B2 | Glycolate oxidase inhibitors for the treatment of disease | XDH, PNPO, AGXT | NPC1 1158/4885RAB9A 3923/4885CTBP2 4861/4885 |
| US-20210171474-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | XDH, PNPO, AGXT | NPC1 1158/4885RAB9A 3923/4885CTBP2 4861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.