Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1479915 | 0.88 | NPC1 (0.55) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL2251562 | 0.82 | RAB9A (0.50) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL17585418 | 0.81 | TSHR (0.42) | L3MBTL1LMNATDP1HTT | |
| SCHEMBL622333 | 0.80 | GSK3B (0.52) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL3070923 | 0.80 | L3MBTL1 (0.52) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL1512094 | 0.80 | NPC1 (0.48) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL4647085 | 0.80 | LMNA (0.52) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL8406795 | 0.80 | L3MBTL1 (0.66) | CTBP2L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL6222420 | 0.79 | VNN1 (0.47) | NPC1RAB9ACTBP2L3MBTL1LMNA | |
| SCHEMBL17124781 | 0.79 | CA2 (0.60) | NPC1RAB9ACTBP2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118185900-A | Transaminase, preparation method and application thereof, and preparation method of amino-containing compound | 爱斯特（成都）生物制药股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118185900-B | Transaminase, preparation method and application thereof, and preparation method of amino-containing compound | 爱斯特（成都）生物制药股份有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-118185900-A | Transaminase, preparation method and application thereof, and preparation method of amino-containing compound | 爱斯特（成都）生物制药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| EP-1931638-A1 | PROCESS FOR THE SYNTHESIS OF COMPOUNDS FOR SELECTIN INHIBITION | Wyeth (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007044475-A1 | PROCESS FOR THE SYNTHESIS OF COMPOUNDS FOR SELECTIN INHIBITION | WYETH (US) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007044475-A1 | PROCESS FOR THE SYNTHESIS OF COMPOUNDS FOR SELECTIN INHIBITION | WYETH (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070082923-A1 | Process for the synthesis of compounds for selectin inhibition | WYETH | 2007-04-12 | — | — | US | disclosed |
| US-20050085644-A1 | Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2005-04-21 | — | — | US | disclosed |
| EP-1472208-A1 | NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003066561-A1 | NOVEL 3-ARYL-2,5-DIHYDROXY-1,4-BENZOQUINONE DERIVATIVES, THEIR PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082923-A1 | Process for the synthesis of compounds for selectin inhibition | SELP, SELE, SELL | NPC1 3962/4885RAB9A 2894/4885CTBP2 2946/4885 |
| US-20050085644-A1 | Novel 3-aryl-2,5-dihydroxy-1,4-benzoquinone derivatives, their preparation method and pharmaceutical compositions containing same | GPR119, UGT1A1, UGT1A3 | NPC1 344/4885RAB9A 1305/4885CTBP2 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.