SCHEMBL14799543

SCHEMBL14799543

CC(C)(C)C1=CC(=NN(Cc2ccccc2)[Si](C)(C)C)C=C(C(C)(C)C)C1=NN(Cc1ccccc1)[Si](C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
AOC3 Q16853 1/20 0.31
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
RIPK1 Q13546 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14799603 0.77 TSHR (0.42) ALDH1A1TSHRAOC3RAB9A
SCHEMBL16492483 0.73 TSHR (0.38) ALDH1A1TSHRAOC3MEN1KMT2A
SCHEMBL15440674 0.73 ALDH1A1 (0.38) ALDH1A1KMT2A
SCHEMBL15440189 0.71 TSHR (0.36) ALDH1A1TSHRAOC3MEN1RAB9A
SCHEMBL16492431 0.70 G6PC1 (0.44) ALDH1A1TSHRAOC3
SCHEMBL14799604 0.70 G6PC1 (0.44) ALDH1A1TSHRAOC3
SCHEMBL14799568 0.69 TSHR (0.41) ALDH1A1TSHRAOC3RAB9AKMT2A
SCHEMBL14800157 0.68 TSHR (0.39) ALDH1A1TSHRAOC3RAB9A
SCHEMBL15439797 0.68 DEPTOR (0.35) ALDH1A1TSHRAOC3MEN1RAB9A
SCHEMBL14799345 0.67 G6PC1 (0.44) ALDH1A1TSHRAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US claimed
US-8962766-B2 Polymers functionalized with polyhydrazone compounds BRIDGESTONE CORPORATION (JP) 2015-02-24 US disclosed
US-20130079463-A1 POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS BRIDGESTONE CORPORATION (JP) 2013-03-28 US disclosed