Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEPTOR | Q8TB45 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492483 | 0.90 | TSHR (0.38) | DEPTORALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15439780 | 0.80 | G6PC1 (0.41) | DEPTORALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL15438962 | 0.77 | DEPTOR (0.35) | DEPTORALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15440189 | 0.72 | TSHR (0.36) | ALDH1A1MEN1KMT2ATSHRCA2 | |
| SCHEMBL14799603 | 0.72 | TSHR (0.42) | ALDH1A1TSHRAOC3NPC1RAB9A | |
| SCHEMBL15440348 | 0.71 | G6PC1 (0.40) | ALDH1A1KMT2ATSHRCA2LRRK2 | |
| SCHEMBL15440347 | 0.71 | G6PC1 (0.40) | ALDH1A1KMT2ATSHRCA2LRRK2 | |
| SCHEMBL15439871 | 0.71 | ALDH1A1 (0.35) | ALDH1A1TSHRL3MBTL1CA2AOC3 | |
| SCHEMBL15440516 | 0.71 | NPC1 (0.36) | ALDH1A1MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL14799604 | 0.71 | G6PC1 (0.44) | ALDH1A1TSHRCA2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |