Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 5/20 | 0.33 |
| ▸ | DHPS | P49366 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ILK | Q13418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477442 | 0.89 | ALPL (0.43) | ALPLKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL1477857 | 0.88 | KDM4E (0.40) | ALPLKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL1478092 | 0.86 | TDP1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16075496 | 0.85 | ALPL (0.34) | ALPLKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1480327 | 0.84 | KDM4E (0.40) | ALPLKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL718683 | 0.84 | ALPL (0.34) | ALPLKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL1222964 | 0.83 | GAA (0.39) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1477994 | 0.83 | ABL1 (0.42) | ALPLKDM4EPKMRCE1ALDH1A1 | |
| SCHEMBL16072637 | 0.81 | CSNK1E (0.36) | KDM4EPKMRCE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16075491 | 0.81 | ALPL (0.40) | ALPLKDM4EPKMRCE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8598085-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | claimed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | claimed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | claimed |
| EP-2573074-B1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8598085-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC. (US) | 2013-12-03 | — | — | US | disclosed |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-05-02 | — | — | US | disclosed |
| EP-2573074-A1 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4- pyrimidinecarboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| US-8357633-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES, LLC (US) | 2013-01-22 | — | — | US | disclosed |
| EP-2311815-B1 | 2-(2-Fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2176239-B1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2311815-A1 | 2-(2-Fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidine carboxylates and their use as herbicides | Dow AgroSciences LLC (US) | 2011-04-20 | — | — | EP | disclosed |
| US-7915200-B2 | 2-(2-fluoro-substituted phenyl)-6-amino-5-chloro-4-pyrimidinecarboxylates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2010-05-13 | — | — | US | disclosed |
| EP-2176239-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009023438-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120621-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | ALPL 3297/4885KDM4E 485/4885PKM 2153/4885 |
| US-20090048109-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | ALPL 3337/4885KDM4E 465/4885PKM 2272/4885 |
| US-20130109573-A1 | 2-(2-FLUORO-SUBSTITUTED PHENYL)-6-AMINO-5-CHLORO-4-PYRIMIDINECARBOXYLATES AND THEIR USE AS HERBICIDES | DDT, DDC, PFAS | ALPL 3297/4885KDM4E 485/4885PKM 2153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.