SCHEMBL1480171

SCHEMBL1480171

CC(C)(C)c1ccc2c(c1)-c1cc(C(C)(C)C)c(-c3ccc(C(F)(F)F)cc3)cc1C2=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.54
CASP3 P42574 2/20 0.54
RAB9A P51151 2/20 0.54
SENP8 Q96LD8 2/20 0.54
SENP7 Q9BQF6 2/20 0.54
SENP6 Q9GZR1 2/20 0.54
ALDH1A1 P00352 1/20 0.54
PLA2G1B P04054 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
ATG4B Q9Y4P1 1/20 0.54
APP P05067 1/20 0.41
MAOB P27338 2/20 0.40
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AKR1C3 P42330 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1482792 0.93 APP (0.42) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1479572 0.89 NPC1 (0.54) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1479830 0.86 NPC1 (0.62) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1480786 0.84 NPC1 (0.51) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1482754 0.77 PTGS2 (0.40) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1481315 0.77 TDP2 (0.40) APPAKR1C3AKR1C2KIF11TDP2
SCHEMBL29163430 0.77 NPC1 (0.81) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL7930867 0.76 ALDH1A1 (0.80) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL13433263 0.76 NPC1 (0.88) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL29926163 0.76 ALDH1A1 (0.80) NPC1CASP3RAB9ASENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed