SCHEMBL1480786

SCHEMBL1480786

COc1ccc(-c2cc3c(cc2C(C)(C)C)-c2cc(C(C)(C)C)ccc2C3=O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
CASP3 P42574 2/20 0.51
SENP8 Q96LD8 2/20 0.51
SENP7 Q9BQF6 2/20 0.51
SENP6 Q9GZR1 2/20 0.51
ALDH1A1 P00352 2/20 0.51
PLA2G1B P04054 1/20 0.51
NFKB1 P19838 1/20 0.51
NFKB2 Q00653 1/20 0.51
RELA Q04206 1/20 0.51
ATG4B Q9Y4P1 1/20 0.51
CASR P41180 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
MAPT P10636 2/20 0.39
ALKBH3 Q96Q83 2/20 0.39
MITF O75030 1/20 0.39
PKM P14618 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480675 0.90 OPRD1 (0.42) NPC1RAB9AL3MBTL1SMN1; SMN2MAPT
SCHEMBL1480171 0.84 NPC1 (0.54) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL1479572 0.84 NPC1 (0.54) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL1479830 0.84 NPC1 (0.62) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL1480784 0.77 NLRP3 (0.36) ALDH1A1MAPTMAOBGRIN2CLMNA
SCHEMBL1482792 0.76 APP (0.42) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL29141426 0.76 MAPT (0.47) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL29163430 0.74 NPC1 (0.81) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL13433263 0.74 NPC1 (0.88) NPC1RAB9AL3MBTL1CASP3SENP8
SCHEMBL7930867 0.74 ALDH1A1 (0.80) NPC1RAB9AL3MBTL1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293856-B2 Process for preparing olefin polymer using mixed catalyst MITSUI CHEMICALS, INC. (JP) 2012-10-23 US disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed