SCHEMBL836333

SCHEMBL836333

O=C(C=Cc1ccccc1)N(O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 7/20 0.70
NPC1 O15118 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HDAC3 O15379 2/20 0.55
HDAC4 P56524 2/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC2 Q92769 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
PLIN1 O60240 2/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 2/20 0.55
MAPT P10636 2/20 0.55
RECQL P46063 2/20 0.55
PLIN5 Q00G26 2/20 0.55
ABHD5 Q8WTS1 2/20 0.55
TNKS O95271 1/20 0.55
HCAR2 Q8TDS4 1/20 0.55
HDAC7 Q8WUI4 1/20 0.55
HDAC10 Q969S8 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL836332 1.00 TRPM8 (0.70) TRPM8NPC1L3MBTL1HDAC3HDAC4
SCHEMBL836743 0.84 TRPM8 (0.76) TRPM8NPC1ALDH1A1LMNAMAPT
SCHEMBL836742 0.84 TRPM8 (0.76) TRPM8NPC1ALDH1A1LMNAMAPT
SCHEMBL837126 0.83 MAOB (0.61) TRPM8L3MBTL1ALDH1A1MAPTBCHE
SCHEMBL837125 0.83 MAOB (0.61) TRPM8L3MBTL1ALDH1A1MAPTBCHE
SCHEMBL10271031 0.82 TRPM8 (1.00) TRPM8NPC1L3MBTL1HDAC3HDAC4
SCHEMBL30532219 0.82 TRPM8 (1.00) TRPM8NPC1L3MBTL1HDAC3HDAC4
SCHEMBL14801940 0.81 LMNA (0.57) TRPM8NPC1L3MBTL1HDAC3HDAC4
SCHEMBL3279797 0.80 TRPM8 (0.44) TRPM8HDAC3HDAC4HDAC1HDAC2
SCHEMBL837372 0.80 TRPM8 (0.44) TRPM8HDAC3HDAC4HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1607446-B1 ORGANIC/INORGANIC HYBRID MATERIAL, COMPOSITION FOR SYNTHESIZING THE SAME AND PROCESS FOR PRODUCING THE HYBRID MATERIAL SEMICONDUCTOR ENERGY LAB (JP) 2016-09-07 EP claimed
CN-101368006-B Organic/inorganic hybrid material, composition for synthesizing the same and process for producing the hybrid material SEMICONDUCTOR ENERGY LAB 2012-05-30 CN claimed
CN-101368006-A Organic/inorganic hybrid material, composition for synthesizing the same and process for producing the hybrid material SEMICONDUCTOR ENERGY LAB (JP) 2009-02-18 CN claimed
CN-1795241-A Organic-inorganic hybrid material, composition for synthesizing the same, and method for producing the same SEMICONDUCTOR ENERGY LAB (JP) 2006-06-28 CN claimed
US-20040265253-A1 Organic-inorganic hybrid material, composition for synthesizing the same, and manufacturing method of the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2004-12-30 US claimed
US-6495247-B1 A COORDINATE BOND BEING A MULTIDENTATE BOND WHERE A MOLECULE BONDS WITH METALLIC ATOM ON SURFACE AND THE METALLIC ATOM IS BETWEEN THE LIGAND ATOMS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-12-17 US claimed
CN-102993051-A Biphenyl and naphthyl-phenyl hydroxamic acid derivatives SIGMA TAU IND FARMACEUTI 2013-03-27 CN disclosed
CN-101650336-B Method for determining copper ions by selenium film modified electrode UNIV ANHUI AGRICULTURE 2012-08-22 CN disclosed
CN-101368006-B Organic/inorganic hybrid material, composition for synthesizing the same and process for producing the hybrid material SEMICONDUCTOR ENERGY LAB 2012-05-30 CN disclosed
US-8143423-B2 N-heterocyclic carbene (NHC) catalyzed synthesis of hydroxamic acids AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-27 US disclosed
US-7879257-B2 comprising a metal oxide and a chelating ligand such as 8-quinolinol; material in which an organic group directly connected to a metal oxide develops a coloring property, a light-emitting property, or semiconductivity SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-02-01 US disclosed
EP-1896399-B1 BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES SIGMA TAU IND FARMACEUTI (IT) 2010-11-17 EP disclosed
US-7728039-B2 Biphenyl and Naphthyl-Phenyl Hydroxamic Acid Derivatives SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2010-06-01 US disclosed
US-6429382-B1 Electrical mounting structure having an elution preventive film MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-08-06 US disclosed
CN-1274950-A Mounting structure, method of manufacturing the same and electrically conductive adhesive MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2000-11-29 CN disclosed
EP-1045437-A2 Mounting structure for electronic component, method of producing the same, and electrically conductive adhesive used therein Matsushita Electric Industrial Co., Ltd. (JP) 2000-10-18 EP disclosed
EP-0896876-A1 FUNCTIONAL MEMBER HAVING MOLECULAR FILM ON THE SURFACE AND PROCESS FOR THE PRODUCTION THEREOF MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-02-17 EP disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
EP-0763512-A1 AIR BAG GAS GENERATING AGENT OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-03-19 EP disclosed
EP-0640686-A2 Method for stabilizing glucose 6-phosphate dehydrogenase KYOWA MEDEX CO.LTD. (JP) 1995-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040265253-A1 Organic-inorganic hybrid material, composition for synthesizing the same, and manufacturing method of the same CAD, ILK, AOC1 TRPM8 1366/4885NPC1 4798/4885L3MBTL1 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.