SCHEMBL3205212

SCHEMBL3205212

C=COCCNC(=O)c1ccccc1C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 2/20 0.47
KDM4E B2RXH2 2/20 0.44
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HPGD P15428 5/20 0.42
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.40
GAA P10253 1/20 0.40
POLB P06746 1/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14802012 0.84 MAPK1 (0.63) MAPK1KMT2AMEN1KDM4ETSHR
SCHEMBL6903284 0.81 TSHR (0.58) KMT2ALMNAMEN1KDM4ETSHR
SCHEMBL15970346 0.78 SMN1; SMN2 (0.65) KMT2ALMNAMEN1NPC1RAB9A
SCHEMBL6564878 0.78 HPGD (0.58) MAPK1KMT2AMEN1KDM4ETSHR
SCHEMBL6515629 0.77 HTT (0.51) KDM4ETSHRHTTHPGDSMN1; SMN2
SCHEMBL461826 0.76 HPGD (0.66) KMT2ALMNAMEN1KDM4EHPGD
SCHEMBL7870127 0.76 HPGD (0.66) KMT2ALMNAMEN1KDM4EHPGD
SCHEMBL9570919 0.76 ALDH1A1 (0.54) KMT2ALMNAMEN1KDM4ETSHR
SCHEMBL8652703 0.76 TSHR (0.53) KMT2AMEN1KDM4ETSHRHTT
SCHEMBL6564787 0.75 HPGD (0.56) MAPK1KMT2ALMNAMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7682651-B2 Method for manufacturing display device CANON KABUSHIKI KAISHA (JP) 2010-03-23 US disclosed
US-20050231795-A1 Method for manufacturing display device CANON KABUSHIKI KAISHA (JP) 2005-10-20 US disclosed