Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802389 | 0.94 | SMN1; SMN2 (0.63) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL7245504 | 0.86 | MAPT (0.69) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL7237063 | 0.84 | HTT (0.76) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL2061754 | 0.79 | ALOX5 (0.77) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL2633343 | 0.79 | ALOX5 (0.77) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL18416918 | 0.79 | HTT (0.68) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL4254980 | 0.79 | TP53 (0.75) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL8713312 | 0.79 | MEN1 (0.81) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| SCHEMBL27451088 | 0.79 | SNCA (0.57) | MAPTKMT2ASMN1; SMN2MEN1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9423776 | 0.78 | ALOX5 (0.75) | MAPTKMT2ASMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9035057-B2 | Dihydroethidine analogues and uses thereof | WASHINGTON UNIVERSITY (US) | 2015-05-19 | — | — | US | disclosed |
| US-9035057-B2 | Dihydroethidine analogues and uses thereof | WASHINGTON UNIVERSITY (US) | 2015-05-19 | — | — | US | disclosed |
| US-20130079522-A1 | DIHYDROETHIDINE ANALOGUES AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079522-A1 | DIHYDROETHIDINE ANALOGUES AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079522-A1 | DIHYDROETHIDINE ANALOGUES AND USES THEREOF | NOX4, QDPR, ROS1 | MAPT 2035/4885KMT2A 4305/4885SMN1; SMN2 3134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.