Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.69 |
| ▸ | RAB9A | P51151 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KLK7 | P49862 | 1/20 | 0.69 |
| ▸ | LCK | P06239 | 4/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.62 |
| ▸ | SCD | O00767 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329390 | 0.91 | MAP3K5 (0.83) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL14807662 | 0.90 | MAP3K5 (0.70) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL14807050 | 0.88 | HTT (0.79) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL14807016 | 0.87 | SCD (0.77) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL13329360 | 0.87 | HSD17B1 (0.74) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL14807437 | 0.86 | MAP3K5 (0.68) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL7127611 | 0.86 | NPC1 (0.71) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL4918066 | 0.86 | MMP13 (0.71) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 | |
| SCHEMBL18472973 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL2483622 | 0.84 | MAP3K5 (0.77) | SMN1; SMN2MAP3K5NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011528-A1 | PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2015-01-08 | — | — | US | disclosed |
| EP-2758384-A1 | PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Yuhan Corporation (KR) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013043001-A1 | PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OR ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011528-A1 | PHENYLIMIDE-CONTAINING BENZOTHIAZOLE DERIVATIVE OF ITS SALT AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | ILK, PKMYT1, PLAUR | SMN1; SMN2 2126/4885MAP3K5 332/4885NPC1 1984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.