Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764129 | 0.68 | MEN1 (0.39) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL573656 | 0.67 | MAPT (0.33) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL21199568 | 0.67 | MAPT (0.43) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL16553920 | 0.65 | ALDH1A1 (0.40) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL31304628 | 0.64 | MAPT (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL31319587 | 0.64 | MAPT (0.45) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL23120910 | 0.63 | L3MBTL1 (0.39) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL10200595 | 0.62 | — | — | |
| SCHEMBL611806 | 0.62 | MAPT (0.47) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL174144 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111196804-B | TGF-beta R1 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-2758402-A1 | PYRROLOPYRIMIDINE AND PURINE DERIVATIVES | Pfizer Inc (US) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013042006-A1 | PYRROLOPYRIMIDINE AND PURINE DERIVATIVES | PFIZER INC. (US) | 2013-03-28 | — | — | WO | disclosed |