Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586891 | 0.85 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL9256544 | 0.84 | ALDH1A1 (0.71) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL278332 | 0.84 | ALDH1A1 (0.76) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL28744511 | 0.84 | ALDH1A1 (0.81) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| SCHEMBL20496958 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL17513182 | 0.84 | ALDH1A1 (0.88) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL31307749 | 0.82 | — | — | |
| Aes-103 SCHEMBL4307459 | 0.81 | ALDH1A1 (0.71) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL3053025 | 0.80 | ALDH1A1 (0.69) | ALDH1A1TSHRMAPTNPC1RAB9A | |
| Aes-103 SCHEMBL1248422 | 0.80 | ALDH1A1 (0.96) | ALDH1A1TSHRMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357878-A1 | METHOD OF PRODUCING 5-HYDROXYMETHYLFURFURAL FROM CARBOHYDRATES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-12-04 | — | — | US | claimed |
| WO-2013043131-A1 | METHOD OF PRODUCING 5-HYDROXYMETHYLFURFURAL FROM CARBOHYDRATES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2013-03-28 | — | — | WO | claimed |
| US-10301275-B2 | Sweet taste modulators | ALTRIA CLIENT SERVICES LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20180265487-A1 | SWEET TASTE MODULATORS | ALTRIA CLIENT SERVICES LLC (US) | 2018-09-20 | — | — | US | disclosed |
| US-20140357878-A1 | METHOD OF PRODUCING 5-HYDROXYMETHYLFURFURAL FROM CARBOHYDRATES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140357878-A1 | METHOD OF PRODUCING 5-HYDROXYMETHYLFURFURAL FROM CARBOHYDRATES | ADH1C, ADH5, ADH1A | ALDH1A1 68/4885TSHR 1770/4885MAPT 3300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.