Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172619 | 1.00 | HTT (0.46) | HTTEPHX1SIGMAR1ADH1BADH1C | |
| SCHEMBL28057484 | 0.89 | — | — | |
| SCHEMBL891398 | 0.89 | SIGMAR1 (0.50) | HTTEPHX1SIGMAR1 | |
| SCHEMBL25086700 | 0.85 | HTT (0.38) | HTTEPHX1SIGMAR1ADH1BADH1C | |
| SCHEMBL26456057 | 0.85 | HTT (0.38) | HTTEPHX1SIGMAR1ADH1BADH1C | |
| SCHEMBL23462691 | 0.82 | HTT (0.36) | HTTEPHX1SIGMAR1 | |
| SCHEMBL104714 | 0.81 | ADH1B (0.44) | HTTEPHX1SIGMAR1ADH1BADH1C | |
| SCHEMBL22899465 | 0.81 | ADH1B (0.44) | HTTEPHX1SIGMAR1ADH1BADH1C | |
| SCHEMBL14176594 | 0.81 | ADH1B (0.44) | HTTEPHX1SIGMAR1ADH1BADH1C | |
| SCHEMBL13995960 | 0.81 | HTT (0.45) | HTTEPHX1SIGMAR1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| WO-2019186164-A1 | FACTOR XIIA INHIBITORS | UNIVERSITY OF LEEDS (GB) | 2019-10-03 | — | — | WO | disclosed |
| US-20170044100-A1 | INHIBITORS OF DRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS | UNIV JOHNS HOPKINS (US) | 2017-02-16 | — | — | US | disclosed |
| EP-2758445-A2 | EPOXY-FUNCTIONAL RESIN COMPOSITIONS | Dow Global Technologies LLC (US) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013043363-A2 | EPOXY-FUNCTIONAL RESIN COMPOSITIONS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044100-A1 | INHIBITORS OF DRUG-RESISTANT MYCOBACTERIUM TUBERCULOSIS | IDO2, IDO1, INMT | HTT 3977/4885EPHX1 2812/4885SIGMAR1 4133/4885 |
| US-10550073-B2 | Benzamide derivative | CYP3A5, ABCB1, CYP2D6 | HTT 2092/4885EPHX1 1725/4885SIGMAR1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.