SCHEMBL891398

SCHEMBL891398

CCC(C)NCC1CCC(CNC(C)CC)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.50
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
PAX8 Q06710 1/20 0.36
SAT1 P21673 1/20 0.35
EPHX1 P07099 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
HSP90AA1 P07900 1/20 0.31
CYP3A4 P08684 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
CASP1 P29466 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28057484 1.00
SCHEMBL14810792 0.89 HTT (0.46) SIGMAR1HTTEPHX1
SCHEMBL172619 0.89 HTT (0.46) SIGMAR1HTTEPHX1
SCHEMBL18756518 0.85 SIGMAR1 (0.40) SIGMAR1KMT2AMEN1HTT
SCHEMBL19936066 0.85 SIGMAR1 (0.40) SIGMAR1KMT2AMEN1HTTSMN1; SMN2
SCHEMBL18756399 0.85 GNAI3 (0.43) SIGMAR1KMT2AHTTPAX8EPHX1
SCHEMBL24638076 0.82 EPHX1 (0.39) SIGMAR1HTTEPHX1SMN1; SMN2
SCHEMBL8467849 0.81 SIGMAR1 (0.47) SIGMAR1KMT2AMEN1HTTPAX8
SCHEMBL21099705 0.81 SIGMAR1 (0.47) SIGMAR1KMT2AMEN1HTTPAX8
SCHEMBL24180077 0.79 SIGMAR1 (0.34) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120080824-A1 CAST POLYURETHANE AND POLYUREA COVERS FOR GOLF BALLS ACUSHNET COMPANY (US) 2012-04-05 US disclosed
US-8013101-B2 Golf ball compositions with improved temperature performance, heat resistance, and resiliency ACUSHNET COMPANY (US) 2011-09-06 US disclosed
US-7888448-B2 Polyurea prepolymer with terminal isocyanate groups, a blocking agent and a polyamine cured with a curing agent, and a polyol; and a second polymeric system comprising an acrylate resin and an initiator ACUSHNET COMPANY (US) 2011-02-15 US disclosed
US-7872087-B2 Golf ball compositions with improved temperature performance, heat resistance, and resiliency ACUSHNET COMPANY (US) 2011-01-18 US disclosed
US-7851561-B2 Interpenetrating polymer networks using blocked polyurethane/polyurea prepolymers for golf ball layers ACUSHNET COMPANY (US) 2010-12-14 US disclosed
US-20100255935-A1 GOLF BALL COMPOSITIONS WITH IMPROVED TEMPERATURE PERFORMANCE, HEAT RESISTANCE, AND RESILIENCY ACUSHNET COMPANY (US) 2010-10-07 US disclosed
US-7700713-B2 Golf ball compositions with improved temperature performance, heat resistance, and resiliency ACUSHNET COMPANY (US) 2010-04-20 US disclosed
US-20090247327-A1 GOLF BALL COMPOSITIONS WITH IMPROVED TEMPERATURE PERFORMANCE, HEAT RESISTANCE, AND RESILIENCY ACUSHNET COMPANY 2009-10-01 US disclosed
US-20090137344-A1 GOLF BALL COMPOSITIONS WITH IMPROVED TEMPERATURE PERFORMANCE, HEAT RESISTANCE, AND RESILIENCY JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2009-05-28 US disclosed
US-7521520-B2 Golf ball compositions with improved temperature performance, heat resistance, and resiliency ACUSHNET COMPANY (US) 2009-04-21 US disclosed
US-7226983-B2 Golf ball compositions with improved temperature performance, heat resistance, and resiliency ACUSHNET COMPANY (US) 2007-06-05 US disclosed
US-20070083029-A1 Golf ball compositions with improved temperature performance, heat resistance, and resiliency ACUSHNET COMPANY 2007-04-12 US disclosed
US-7163994-B2 Golf ball composition with improved temperature performance, heat resistance and resiliency ACUSHNET COMPANY (US) 2007-01-16 US disclosed
US-7157527-B2 Interpenetrating polymer networks using blocked polyurethane/polyurea prepolymers for golf ball layers ACUSHNET COMPANY (US) 2007-01-02 US disclosed
US-20060153999-A1 Cast urethane process WU SHENSHEN 2006-07-13 US disclosed
US-20050228160-A1 Golf ball compositions with improved temperature performance, heat resistance, and resiliency JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-10-13 US disclosed
US-20050228146-A1 Golf ball compositions with improved temperature performance, heat resistance, and resiliency JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-10-13 US disclosed
US-20050009636-A1 Interpenetrating polymer networks using blocked polyurethane/polyurea prepolymers for golf ball layers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20050009635-A1 Interpenetrating polymer networks using blocked polyurethane/polyurea prepolymers for golf ball layers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US disclosed
US-20040266558-A1 Interpenetrating polymer networks using blocked polyurethane/polyurea prepolymers for golf ball layers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-12-30 US disclosed