Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14813746 | 1.00 | STING1 (0.61) | STING1KDM4EFFAR1HTT | |
| SCHEMBL14813748 | 1.00 | STING1 (0.61) | STING1KDM4EFFAR1HTT | |
| SCHEMBL2614589 | 0.92 | STING1 (0.63) | STING1FFAR1HTT | |
| SCHEMBL17317320 | 0.92 | STING1 (0.63) | STING1FFAR1HTT | |
| SCHEMBL17317318 | 0.92 | STING1 (0.63) | STING1FFAR1HTT | |
| SCHEMBL17317364 | 0.86 | MDM2 (0.67) | STING1 | |
| SCHEMBL2098416 | 0.86 | MDM2 (0.67) | STING1 | |
| SCHEMBL17317150 | 0.86 | STING1 (0.63) | STING1FFAR1 | |
| SCHEMBL17317152 | 0.86 | STING1 (0.63) | STING1FFAR1 | |
| SCHEMBL29921322 | 0.86 | MDM2 (0.67) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664238-B2 | Indenoisoquinolinone derivatives, manufacturing method and medical use thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2014-03-04 | — | — | US | disclosed |
| US-20130085140-A1 | INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085140-A1 | INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF | MYLK, PTGIS, PGF | STING1 2120/4885KDM4E 2111/4885FFAR1 2387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.