Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10510746 | 0.85 | ALOX5 (0.59) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL12459917 | 0.85 | L3MBTL1 (0.50) | ALDH1A1GRIN2BPOLBHPGDSMN1; SMN2 | |
| SCHEMBL14543057 | 0.84 | ALDH1A1 (0.68) | ALDH1A1GRIN2BMEN1KMT2APOLB | |
| SCHEMBL7121816 | 0.84 | MEN1 (0.78) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL19609094 | 0.82 | ALDH1A1 (0.54) | ALDH1A1GRIN2BMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27253358 | 0.81 | MEN1 (0.65) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL14817926 | 0.81 | ALDH1A1 (0.71) | ALDH1A1GRIN2BMEN1KMT2APOLB | |
| SCHEMBL14297348 | 0.81 | ALDH1A1 (0.71) | ALDH1A1GRIN2BMEN1KMT2APOLB | |
| SCHEMBL17572089 | 0.80 | MEN1 (0.69) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL17572094 | 0.80 | MEN1 (0.69) | ALDH1A1MEN1KMT2APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802636-B1 | PI3 KINASES INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2013-03-27 | — | — | EP | disclosed |