Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25402344 | 0.80 | HDAC1 (0.57) | HDAC1CYP1A2CYP2C19PTGS1PTGS2 | |
| SCHEMBL2899293 | 0.77 | HDAC1 (0.60) | HDAC1CYP1A2CYP3A4CYP2C19CDC7 | |
| SCHEMBL27432924 | 0.73 | HDAC1 (0.56) | HDAC1CYP19A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL10153571 | 0.73 | HDAC1 (0.52) | HDAC1CYP19A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24011415 | 0.73 | HDAC1 (0.48) | HDAC1CYP19A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20592359 | 0.73 | HDAC1 (0.49) | HDAC1CYP19A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1482469 | 0.69 | HDAC8 (0.52) | HDAC1CYP19A1HDAC3HDAC2HDAC10 | |
| SCHEMBL2895467 | 0.68 | CDC7 (0.61) | HDAC1CYP19A1CDC7HDAC3HDAC2 | |
| SCHEMBL3320095 | 0.67 | PTGS1 (0.46) | HDAC1CYP1A2CYP3A4CYP2C19PTGS1 | |
| SCHEMBL2959419 | 0.67 | HDAC1 (0.46) | HDAC1CYP19A1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077365-A1 | PREPARATION OF ORGANOSILICON-CONTAINING TRIAZOLES | MCMASTER UNIVERSITY (CA) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110077365-A1 | PREPARATION OF ORGANOSILICON-CONTAINING TRIAZOLES | ATR, RNF31, RNF5 | HDAC1 3827/4885CYP19A1 1176/4885CYP1A2 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.