Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18944283 | 0.85 | KDM4E (0.45) | PTGS2SMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL27129683 | 0.80 | KDM4E (0.48) | SMN1; SMN2ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL1682127 | 0.78 | FLT3 (0.45) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL10983833 | 0.77 | KDM4E (0.53) | SMN1; SMN2ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL14822776 | 0.76 | PTGS2 (0.54) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11622217 | 0.76 | PTGS2 (0.57) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL14822769 | 0.76 | PTGS2 (0.35) | PTGS2HTTMDM2CCR1CCR5 | |
| SCHEMBL28535188 | 0.75 | L3MBTL1 (0.38) | PTGS2GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL11591603 | 0.74 | NPC1 (0.67) | SMN1; SMN2ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL12776157 | 0.74 | NPC1 (0.46) | SMN1; SMN2ALDH1A1KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170162804-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2017-06-08 | — | — | US | disclosed |
| US-8410269-B2 | Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-04-02 | — | — | US | disclosed |
| US-20110313161-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-22 | — | — | US | disclosed |
| US-20110313162-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | NATIONAL TSING HUA UNIVERSITY (TW) | 2011-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170162804-A1 | ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE EMPLOYING THE SAME | METTL3, MEN1, L1CAM | PTGS2 4124/4885GABRA1 3210/4885GABRG2 3657/4885 |
| US-20110313161-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | LIG3, LIG4, LIG1 | PTGS2 2630/4885GABRA1 2372/4885GABRG2 2163/4885 |
| US-20110313162-A1 | PHOSPHORESCENT IRIDIUM COMPLEX WITH NON-CONJUGATED CYCLOMETALATED LIGANDS, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF | LIG3, LIG4, LIG1 | PTGS2 2630/4885GABRA1 2372/4885GABRG2 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.