SCHEMBL27129683

SCHEMBL27129683

Cc1nc(-c2ccccn2)n(C)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.48
NPC1 O15118 5/20 0.48
LMNA P02545 4/20 0.48
HTT P42858 3/20 0.48
RAB9A P51151 3/20 0.48
POLB P06746 2/20 0.48
BLM P54132 2/20 0.48
MAPK1 P28482 2/20 0.48
MAPT P10636 2/20 0.48
APAF1 O14727 1/20 0.48
KDM4A O75164 1/20 0.48
TDP2 O95551 1/20 0.48
EGFR P00533 1/20 0.48
THRB P10828 1/20 0.48
PPARG P37231 1/20 0.48
CASP3 P42574 1/20 0.48
RECQL P46063 1/20 0.48
DUSP3 P51452 1/20 0.48
GALK1 P51570 1/20 0.48
CASP7 P55210 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10983833 0.82 KDM4E (0.53) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL18944283 0.81 KDM4E (0.45) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL14822767 0.80 PTGS2 (0.46) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL11591603 0.80 NPC1 (0.67) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL23130743 0.77 KDM4E (0.47) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL11590779 0.77 NPC1 (0.54) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL12776157 0.76 NPC1 (0.46) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL10513619 0.73 NPC1 (0.46) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL679761 0.72 NR1H3 (0.68) KDM4ENPC1LMNAHTTRAB9A
SCHEMBL24409726 0.72 L3MBTL1 (0.52) KDM4ENPC1LMNAHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240376513-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-11-14 US disclosed
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
EP-4328232-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER I-SENS, INC. (KR) 2024-02-28 EP disclosed
CN-117242084-A Electrochemical biosensor comprising transition metal complex or redox polymer or sensing membrane for electrochemical biosensor 爱-森新株式会社 2023-12-15 CN disclosed
WO-2022225313-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER 주식회사 아이센스 2022-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240376513-A1 ELECTROCHEMICAL BIOSENSOR, OR SENSING MEMBRANE FOR ELECTROCHEMICAL BIOSENSOR CONTAINING TRANSITION METAL COMPLEX OR OXIDATION-REDUCTION POLYMER OXA1L, PDK1, SLC2A3 KDM4E 3047/4885NPC1 4604/4885LMNA 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.