Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | AOC2 | O75106 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13410003 | 0.87 | CTDSP1 (0.38) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL3693612 | 0.77 | CPT2 (0.45) | CA12CA1CA2CA9L3MBTL1 | |
| SCHEMBL14822903 | 0.77 | MAPK1 (0.52) | PKMCA12CA1CA2CA9 | |
| SCHEMBL14822987 | 0.73 | PKM (0.54) | PKMALDH1A1MEN1KMT2A | |
| SCHEMBL4892738 | 0.73 | AOC2 (0.50) | PKML3MBTL1CTDSP1AOC2MAPT | |
| SCHEMBL2643881 | 0.72 | ALDH1A1 (0.56) | L3MBTL1CTDSP1AOC2ALDH1A1POLB | |
| SCHEMBL6375568 | 0.71 | PKM (0.66) | PKML3MBTL1LMNAALDH1A1POLB | |
| SCHEMBL14822898 | 0.71 | ALDH1A1 (0.58) | PKML3MBTL1LMNAMAPTALDH1A1 | |
| SCHEMBL14823033 | 0.70 | CYP2C9 (0.64) | PKMCA12CA1CA2CA9 | |
| SCHEMBL14823053 | 0.69 | FFAR1 (0.48) | PKMLMNAMAPTPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |