Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 11/20 | 0.47 |
| ▸ | MMP9 | P14780 | 11/20 | 0.47 |
| ▸ | MMP1 | P03956 | 6/20 | 0.44 |
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | MMP14 | P50281 | 6/20 | 0.44 |
| ▸ | MMP25 | Q9NPA2 | 5/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13410015 | 0.91 | MMP2 (0.44) | MMP2MMP9MMP1MMP3MMP8 | |
| Trifluoroacetic Acid SCHEMBL3683491 | 0.85 | MMP2 (0.41) | MMP2MMP9MMP1MMP3MMP8 | |
| Trifluoroacetic Acid SCHEMBL3683485 | 0.85 | MMP2 (0.41) | MMP2MMP9MMP1MMP3MMP8 | |
| SCHEMBL14823019 | 0.82 | S1PR1 (0.47) | S1PR2S1PR1S1PR3S1PR4ALDH1A1 | |
| SCHEMBL14823011 | 0.80 | MMP9 (0.67) | MMP2MMP9MMP1MMP3MMP8 | |
| SCHEMBL14823059 | 0.79 | IKBKB (0.39) | MMP2MMP9MMP14ALDH1A1TAS1R3 | |
| SCHEMBL3683488 | 0.77 | MMP2 (0.38) | MMP2MMP9MMP1MMP3MMP8 | |
| SCHEMBL13444482 | 0.76 | TAS1R3 (0.37) | MMP2MMP9MMP1S1PR2S1PR1 | |
| SCHEMBL14823034 | 0.74 | ALDH1A1 (0.40) | MMP2MMP9MMP3MMP14MMP13 | |
| SCHEMBL3676623 | 0.74 | MMP9 (0.63) | MMP2MMP9MMP1MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |