SCHEMBL14828485

SCHEMBL14828485

C=C(C)C(=O)OC(C)(c1ccccc1)c1ccc(C(F)(F)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
BACE1 P56817 1/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
KIF11 P52732 2/20 0.39
ELANE P08246 1/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CYP1A1 P04798 1/20 0.38
MAOB P27338 1/20 0.38
CYP1B1 Q16678 1/20 0.38
TRPV6 Q9H1D0 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3180129 0.90 CYP2C19 (0.46) ALDH1A1ELANECYP2C19HIF1ACES1
SCHEMBL15648916 0.88 KCNN4 (0.46) ALDH1A1NPC1RAB9AKIF11ELANE
SCHEMBL14827356 0.86 ELANE (0.40) ALDH1A1TSHRNPC1RAB9AKIF11
SCHEMBL27496577 0.83 CYP2C19 (0.43) ALDH1A1TSHRBACE1ELANECYP2C19
SCHEMBL14828484 0.83 SRPK1 (0.35) BACE1RAB9ANR4A1NR4A2NR4A3
SCHEMBL14828488 0.82 NPC1 (0.37) ALDH1A1TSHRBACE1NPC1RAB9A
SCHEMBL14827400 0.82 CES2 (0.41) ALDH1A1BACE1NR4A1NR4A2NR4A3
SCHEMBL14828493 0.81 CES2 (0.33) ALDH1A1BACE1NR4A1NR4A2NR4A3
SCHEMBL14828490 0.81 CES2 (0.33) ALDH1A1BACE1NPC1RAB9ANR4A1
SCHEMBL14648216 0.80 ELANE (0.42) ALDH1A1TSHRBACE1ELANECYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9201300-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-12-01 US disclosed
US-9140988-B2 Positive resist composition, monomer, polymer, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-09-22 US disclosed
US-9040223-B2 Resist composition, patterning process and polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-05-26 US disclosed
US-20140178820-A1 RESIST COMPOSITION, PATTERNING PROCESS AND POLYMER SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-26 US disclosed
US-20140178818-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-26 US disclosed
US-20140162188-A1 POSITIVE RESIST COMPOSITION, MONOMER, POLYMER, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-06-12 US disclosed
US-20130084527-A1 POSITIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-04 US disclosed