SCHEMBL1482867

SCHEMBL1482867

CCc1ccccc1-c1ccc2c(c1)Cc1cc(-c3ccccc3CC)ccc1-2.COc1ccc(-c2ccc3c(c2)Cc2cc(-c4ccc(OC)cc4)ccc2-3)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.45
BACE1 P56817 3/20 0.45
ALDH1A1 P00352 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
HPGD P15428 1/20 0.45
TDP2 O95551 1/20 0.43
PDK2 Q15119 1/20 0.43
ADORA1 P30542 1/20 0.43
CYP3A4 P08684 1/20 0.42
PTGES O14684 1/20 0.42
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42
BCR P11274 1/20 0.42
CYP24A1 Q07973 2/20 0.42
FFAR4 Q5NUL3 2/20 0.42
FFAR1 O14842 1/20 0.42
CYP27A1 Q02318 1/20 0.42
TEK Q02763 1/20 0.42
MMP12 P39900 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1906811 0.87 TRPA1 (0.48) ALDH1A1MAPTKDM4EHPGDTDP2
SCHEMBL1482762 0.84 RAB9A (0.48) ALDH1A1MAPTKDM4EHPGDCYP3A4
SCHEMBL1480944 0.84 ALDH1A1 (0.56) ACHEBACE1ALDH1A1MAPTKDM4E
SCHEMBL13358868 0.82 CYP3A4 (0.55) ACHEBACE1ALDH1A1MAPTKDM4E
SCHEMBL18932233 0.82 CYP3A4 (0.55) ACHEBACE1ALDH1A1MAPTKDM4E
SCHEMBL33722042 0.82 CYP3A4 (0.55) ACHEBACE1ALDH1A1MAPTKDM4E
SCHEMBL13675365 0.81 ABL1 (0.56) BACE1ALDH1A1MAPTKDM4EHPGD
SCHEMBL27824487 0.74 MEN1 (0.49) BACE1ALDH1A1MAPTKDM4EHPGD
SCHEMBL23812923 0.73 CYP24A1 (0.48) MAPTHPGDCYP3A4ABL1ABCB1
SCHEMBL9290083 0.73 ABL1 (0.59) ALDH1A1MAPTHPGDCYP3A4ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed