Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14830272 | 1.00 | MTNR1A (0.52) | MTNR1AMTNR1BL3MBTL1MAPTALDH1A1 | |
| SCHEMBL14838802 | 0.85 | MTNR1A (0.38) | MTNR1AMTNR1BL3MBTL1MAPTALDH1A1 | |
| SCHEMBL14838786 | 0.84 | SYK (0.44) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL15422769 | 0.81 | ALDH1A1 (0.47) | MTNR1AMTNR1BL3MBTL1ALDH1A1 | |
| SCHEMBL15422770 | 0.81 | ALDH1A1 (0.47) | MTNR1AMTNR1BL3MBTL1ALDH1A1 | |
| SCHEMBL14838694 | 0.80 | KCNN4 (0.35) | MTNR1AMTNR1BL3MBTL1MAPTALDH1A1 | |
| SCHEMBL14830347 | 0.79 | HPGD (0.44) | ALDH1A1 | |
| SCHEMBL14830582 | 0.79 | ALOX15 (0.38) | MTNR1AMTNR1BL3MBTL1MAPTALDH1A1 | |
| SCHEMBL15422598 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1B | |
| SCHEMBL15422596 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |