SCHEMBL14830582

SCHEMBL14830582

NC[C@@H](CCl)OC(=O)Oc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.38
USP2 O75604 1/20 0.36
NSD2 O96028 1/20 0.36
SLC1A3 P43003 1/20 0.36
ATM Q13315 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GABBR2 O75899 1/20 0.34
GABBR1 Q9UBS5 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
CYP19A1 P11511 1/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14838802 0.81 MTNR1A (0.38) ALOX15NSD2SLC1A3ATML3MBTL1
SCHEMBL14830272 0.79 MTNR1A (0.52) L3MBTL1ALDH1A1MAPTMTNR1AMTNR1B
SCHEMBL14830271 0.79 MTNR1A (0.52) L3MBTL1ALDH1A1MAPTMTNR1AMTNR1B
SCHEMBL14830332 0.77 USP2 (0.35) ALOX15USP2ATML3MBTL1TDP1
SCHEMBL14720810 0.77 USP2 (0.35) ALOX15USP2NSD2ATML3MBTL1
SCHEMBL29051390 0.77 USP2 (0.35) ALOX15USP2NSD2ATML3MBTL1
SCHEMBL14830782 0.77 ALOX15 (0.40) ALOX15USP2NSD2SLC1A3ATM
SCHEMBL14838694 0.76 KCNN4 (0.35) ALOX15ATML3MBTL1TDP1ALDH1A1
SCHEMBL14830333 0.76 ALDH1A1 (0.43) TDP1ALDH1A1MAPT
SCHEMBL6881543 0.75 MTNR1A (0.50) ALOX15MAPTMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013046211-A1 PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF SYMED LABS LIMITED (IN) 2013-04-04 WO disclosed