Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14815270 | 1.00 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1HSD11B1TEAD1PRKAB2 | |
| SCHEMBL14815072 | 0.91 | L3MBTL3 (0.55) | L3MBTL3L3MBTL1TEAD1SLC6A5KMT2A | |
| SCHEMBL14833207 | 0.90 | HSD11B1 (0.53) | L3MBTL3L3MBTL1HSD11B1KMT2AMEN1 | |
| SCHEMBL14815282 | 0.90 | HSD11B1 (0.53) | L3MBTL3L3MBTL1HSD11B1KMT2AMEN1 | |
| SCHEMBL14833216 | 0.90 | CCR2 (0.54) | L3MBTL3L3MBTL1HSD11B1KMT2AMEN1 | |
| SCHEMBL14815069 | 0.90 | CCR2 (0.54) | L3MBTL3L3MBTL1HSD11B1KMT2AMEN1 | |
| SCHEMBL14814591 | 0.87 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1TEAD1SLC6A5KMT2A | |
| SCHEMBL14833257 | 0.87 | L3MBTL3 (0.50) | L3MBTL3L3MBTL1TEAD1SLC6A5KMT2A | |
| SCHEMBL14815209 | 0.84 | L3MBTL3 (0.51) | L3MBTL3L3MBTL1SLC6A5KMT2AMEN1 | |
| SCHEMBL14815389 | 0.82 | TRPV4 (0.53) | L3MBTL3L3MBTL1KMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049164-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS | ABBVIE INC. (US) | 2013-04-04 | — | — | WO | disclosed |