Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TACR3 | P29371 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14815191 | 0.85 | GPR119 (0.43) | HCRTR1TACR3 | |
| SCHEMBL14815189 | 0.85 | GPR119 (0.43) | HCRTR1TACR3 | |
| SCHEMBL14815181 | 0.79 | MGLL (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL14815085 | 0.79 | MGLL (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL14815083 | 0.79 | MGLL (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL7107806 | 0.78 | MMP1 (0.47) | HCRTR1HCRTR2TACR3MMP1 | |
| SCHEMBL7105199 | 0.78 | MMP1 (0.47) | HCRTR1HCRTR2TACR3MMP1 | |
| SCHEMBL14815060 | 0.77 | HRH3 (0.39) | HCRTR1HCRTR2HRH3TACR3KCNH2 | |
| SCHEMBL14814968 | 0.77 | HRH3 (0.39) | HCRTR1HCRTR2HRH3TACR3KCNH2 | |
| SCHEMBL5274039 | 0.76 | MMP1 (0.44) | HCRTR1HCRTR2HRH3KCNH2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049164-A1 | SUBSTITUTED OCTAHYDROPYRROLO[1,2-a]PYRAZINES AS CALCIUM CHANNEL BLOCKERS | ABBVIE INC. (US) | 2013-04-04 | — | — | WO | disclosed |