Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107806 | 1.00 | MMP1 (0.47) | MMP1FPR2PROKR1LIPEEGFR | |
| SCHEMBL5274039 | 0.92 | MMP1 (0.44) | MMP1FPR2PROKR1LIPEEGFR | |
| SCHEMBL5318377 | 0.92 | MMP1 (0.52) | MMP1FPR2PROKR1LIPEEGFR | |
| SCHEMBL20137537 | 0.84 | LIPE (0.45) | LIPELIPGHSD11B1HMOX1NAMPT | |
| SCHEMBL18077130 | 0.84 | LIPE (0.45) | LIPELIPGHSD11B1HMOX1NAMPT | |
| SCHEMBL596068 | 0.84 | LIPG (0.43) | LIPGHSD11B1HMOX1NAMPTGPR119 | |
| SCHEMBL16973134 | 0.84 | LIPG (0.43) | LIPGHSD11B1HMOX1NAMPTGPR119 | |
| SCHEMBL596069 | 0.84 | LIPG (0.43) | LIPGHSD11B1HMOX1NAMPTGPR119 | |
| SCHEMBL5672385 | 0.83 | GPR119 (0.58) | MMP1GPR119 | |
| SCHEMBL5672367 | 0.83 | GPR119 (0.58) | MMP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347990-A2 | PEPTIDE MIT INHIBIERENDER AKTIVITÄT ZUR PRODUKTION VON STICKSTOFFMONOXID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002055541-A2 | PEPTIDES HAVING INHIBITING ACTIVITY ON THE PRODUCTION OF NITRIC OXIDE | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-07-18 | — | — | WO | disclosed |