Etiocholanolone

Etiocholanolone

SCHEMBL148334

C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 5/20 1.00
GPBAR1 Q8TDU6 4/20 1.00
LMNA P02545 3/20 1.00
CYP3A4 P08684 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
SHBG P04278 2/20 1.00
SERPINA6 P08185 2/20 1.00
MAPK1 P28482 2/20 1.00
HSD17B3 P37058 1/20 1.00
PMP22 Q01453 1/20 1.00
AKR1B10 O60218 1/20 1.00
AKR1B1 P15121 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
NFKB1 P19838 1/20 1.00
CYP2C19 P33261 1/20 1.00
ALDH1A1 P00352 1/20 0.67
TP53 P04637 1/20 0.67
MAPT P10636 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androsterone SCHEMBL10273502 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL269982 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL13175783 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Epiandrosterone SCHEMBL295167 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL12811704 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL15426610 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL23031469 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL9940929 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL19750468 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL21114416 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 911 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-05-28 US claimed
EP-4740024-A1 ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS The University Court Of The University of Edinburgh (GB) 2026-05-13 EP claimed
US-12569501-B2 Neurosteroids and enantiomers thereof for the prevention and treatment of neurodegenerative conditions WASHINGTON UNIVERSITY (US) 2026-03-10 US claimed
US-20250213589-A1 METHODS AND COMPOSITIONS FOR TESTOSTERONE PRODUCTION Maximus Health, Inc. (US) 2025-07-03 US claimed
EP-4562182-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2025-06-04 EP claimed
WO-2025096781-A1 METHODS AND COMPOSITIONS FOR PROVIDING CUSTOMIZED SKIN REGIMENS VIBRANT HOLDINGS, LLC (US) 2025-05-08 WO claimed
WO-2025008638-A1 ENDOMETRIOSIS MARKERS AND METHODS OF DIAGNOSING ENDOMETRIOSIS THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) 2025-01-09 WO claimed
US-20240041898-A9 NEUROSTEROIDS AND ENANTIOMERS THEREOF FOR THE PREVENTION AND TREATMENT OF NEURODEGENERATIVE CONDITIONS WASHINGTON UNIVERSITY 2024-02-08 US claimed
WO-2024023324-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2024-02-01 WO claimed
WO-2023083020-A1 USE OF SERUM METABOLIC MARKER FOR DETECTING EGFR MUTATION AND DETECTION SYSTEM 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 2023-05-19 WO claimed
WO-1996016680-A1 PHOSPHOCHOLINE DRUG DERIVATIVES AMUR RESEARCH CORP. (US) 1996-06-06 WO claimed
WO-1995010291-A1 METHODS FOR COLLECTION AND CRYOPRESERVATION OF HUMAN GRANULOCYTES CELLPRO II (US) 1995-04-20 WO claimed
US-5006517-A Administering 3-oxo or hydroxy substituted 5-beta-androstan-17-one PROGENICS, INC. (US) 1991-04-09 US claimed
US-4897390-A 3-METHYLANDROSTAN-17-ONE; CONCURRENT SUPPRESSION OF CALORIC INTAKE AND INCREASE OF CALORIC EXPENDITURE HUMANETICS CORPORATION 1990-01-30 US claimed
US-4722899-A INDUCE IMMUNOLOGICAL TOLERANCE TO SECOND ANTIGEN THEN IMMUNIZING WITH FIRST ANTIGEN Hamaoka, Toshiyuki (JP) 1988-02-02 US claimed
US-4628052-A Pharmaceutical compositions containing dehydroepiandrosterone and other anesthetic steroids in the treatment of arthritis and other joint disabilities PEAT RAYMOND F 1986-12-09 US claimed
EP-0149220-A2 Treatment of obesity, diabetes and other symptoms of hypercorticoidism using etiocholanolones The Jackson Laboratory (US) 1985-07-24 EP claimed
EP-0148436-A1 Treatment of diabetes and other symptoms of hypercorticoidism using a synergistic combination of etiocholanolones and estrogen The Jackson Laboratory (US) 1985-07-17 EP claimed
US-4507289-A Treatment of diabetes and other symptoms of hypercorticoidism using a synergistic combination of etiocholanolones and estrogen PROGENICS, INC. (US) 1985-03-26 US claimed
US-4321208-A Preparation of directly iodinated steroid hormones and related compounds SAHADEVAN VELAYUDHAN 1982-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213589-A1 METHODS AND COMPOSITIONS FOR TESTOSTERONE PRODUCTION SHBG, AR, CYP19A1 G6PD 997/4885GPBAR1 466/4885LMNA 3750/4885
US-12569501-B2 Neurosteroids and enantiomers thereof for the prevention and treatment of neurodegenerative conditions ATG13, GSK3B, HSD11B1 G6PD 1662/4885GPBAR1 623/4885LMNA 3367/4885
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF SHBG, HSD11B2, HSD11B1 G6PD 1366/4885GPBAR1 650/4885LMNA 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.