Androsterone

Androsterone

SCHEMBL598976

C[C@]12CCC(O)CC1CC[C@@H]1[C@H]2CC[C@]2(C)C(=O)CC[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ G6PD P11413 5/20 1.00
▸ GPBAR1 Q8TDU6 4/20 1.00
▸ LMNA P02545 3/20 1.00
▸ CYP3A4 P08684 3/20 1.00
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ SHBG P04278 2/20 1.00
▸ SERPINA6 P08185 2/20 1.00
▸ MAPK1 P28482 2/20 1.00
▸ HSD17B3 P37058 1/20 1.00
▸ PMP22 Q01453 1/20 1.00
▸ AKR1B10 O60218 1/20 1.00
▸ AKR1B1 P15121 1/20 1.00
▸ CYP2D6 P10635 1/20 1.00
▸ TSHR P16473 1/20 1.00
▸ NFKB1 P19838 1/20 1.00
▸ CYP2C19 P33261 1/20 1.00
▸ ALDH1A1 P00352 1/20 0.67
▸ TP53 P04637 1/20 0.67
▸ MAPT P10636 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Androsterone SCHEMBL2383099 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL16258913 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Etiocholanolone SCHEMBL148334 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL15369415 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL12968676 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL23031469 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL16385946 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL8253266 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL21114416 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1
Androsterone SCHEMBL13641972 1.00 G6PD (1.00) G6PDGPBAR1LMNACYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 — — US claimed
EP-2938654-B1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES OREAL (FR) 2016-08-24 — — EP claimed
US-20160038536-A1 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF TRAUMA-INDUCED NEUROPATHOLOGY AND NEURODEGENERATION SAPNA LIFE SCIENCES CORPORATION (CA) 2016-02-11 — — US claimed
US-20150342868-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES LOREAL (FR) 2015-12-03 — — US claimed
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-12 — — US claimed
EP-2938402-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-04 — — EP claimed
EP-2938654-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-04 — — EP claimed
WO-2014108808-A2 PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF TRAUMA-INDUCED NEUROPATHOLOGY AND NEURODEGENERATION HENRY JAMES LORNE (CA) 2014-07-17 — — WO claimed
WO-2014108809-A2 MULTIPLE-COMPONENT PHARMACEUTICAL FORMULATIONS AND METHODS FOR THEIR USE IN TREATING NEUROPATHOLOGY AND NEURODEGENERATION CAUSED BY TRAUMATIC INJURY HENRY JAMES LORNE (CA) 2014-07-17 — — WO claimed
WO-2014107794-A1 FORMULATIONS AND METHODS FOR THEIR USE IN TREATMENT OF NEUROPATHOLOGY AND NEURODEGENERATION AS A RESULT OF TRAUMATIC INJURY SAPNA LIFE SCIENCES CORP. (CA) 2014-07-17 — — WO claimed
WO-2000056757-A1 IMMUNOMODULATORY STEROIDS, IN PARTICULAR THE HEMIHYDRATE OF 16.ALPHA.-BROMOEPIANDROSTERONE HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2000-09-28 — — WO claimed
WO-2000032176-A2 USE OF 17-KETOSTEROIDS FOR THE TREATMENT OF TOXOPLASMOSIS AND CRYPTOSPORIDOSIS HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2000-06-08 — — WO claimed
WO-2000032201-A2 USE OF 17-KETOSTEROIDS FOR THE TREATMENT OF MALARIA AND TRYPANOSOMIASIS HOLLIS-EDEN PHARMACEUTICALS, INC. (US) 2000-06-08 — — WO claimed
EP-0659072-A1 PHARMACEUTICAL EMULSIONS CONTAINING BIOACTIVE STEROIDS Pharmacia AB (SE) 1995-06-28 — — EP claimed
WO-1995001162-A1 PHARMACEUTICAL EMULSIONS CONTAINING BIOACTIVE STEROIDS PHARMACIA AB (SE) 1995-01-12 — — WO claimed
US-4897390-A 3-METHYLANDROSTAN-17-ONE; CONCURRENT SUPPRESSION OF CALORIC INTAKE AND INCREASE OF CALORIC EXPENDITURE HUMANETICS CORPORATION 1990-01-30 — — US claimed
EP-0148436-B1 TREATMENT OF DIABETES AND OTHER SYMPTOMS OF HYPERCORTICOIDISM USING A SYNERGISTIC COMBINATION OF ETIOCHOLANOLONES AND ESTROGEN The Jackson Laboratory (US) 1988-10-12 — — EP claimed
EP-0149220-A2 Treatment of obesity, diabetes and other symptoms of hypercorticoidism using etiocholanolones The Jackson Laboratory (US) 1985-07-24 — — EP claimed
EP-0148436-A1 Treatment of diabetes and other symptoms of hypercorticoidism using a synergistic combination of etiocholanolones and estrogen The Jackson Laboratory (US) 1985-07-17 — — EP claimed
US-4507289-A Treatment of diabetes and other symptoms of hypercorticoidism using a synergistic combination of etiocholanolones and estrogen PROGENICS, INC. (US) 1985-03-26 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A G6PD 4611/4885GPBAR1 672/4885LMNA 3666/4885
US-20150342868-A1 MOLECULARLY IMPRINTED POLYMER OF SOL-GEL TYPE FOR SELECTIVELY TRAPPING ODOROUS MOLECULES TAS2R30, TAS1R1, TAS2R10 G6PD 3970/4885GPBAR1 2938/4885LMNA 4639/4885
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES OR10J3, OR51E2, MSMO1 G6PD 3301/4885GPBAR1 2160/4885LMNA 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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