Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14836632 | 0.84 | GABRP (0.40) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL14836631 | 0.84 | GABRP (0.40) | ACHEBACE1GABRPGABRDGABRA1 | |
| SCHEMBL2545649 | 0.75 | ACHE (0.58) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| SCHEMBL1941417 | 0.75 | ACHE (0.58) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| Methyl Alcohol SCHEMBL4653215 | 0.74 | ACHE (0.56) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| SCHEMBL10970806 | 0.73 | ACHE (0.46) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| SCHEMBL1259562 | 0.73 | ACHE (0.46) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| SCHEMBL900317 | 0.71 | GABRP (0.48) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| SCHEMBL17021602 | 0.71 | GABRP (0.48) | ACHEBACE1CHRM1AKR1A1CHRM3 | |
| SCHEMBL900319 | 0.71 | GABRP (0.48) | ACHEBACE1CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729294-B2 | Process for producing optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20130137880-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-30 | — | — | US | disclosed |
| EP-2578566-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | Sumitomo Chemical Company Limited (JP) | 2013-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137880-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND | HPD, GRHPR, HAAO | ACHE 3914/4885BACE1 2620/4885CHRM1 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.